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杨红卫

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杨红卫,博士,教授,硕士生导师。2004年毕业于中山大学中山医学院,获医学博士学位。2006年至2008年在美国LSUHSC做博士后,从事神经科学研究。自1998年开始,一直从事神经科学领域的研究,在此领域发表了50余篇研究论文,其中17篇论文在J Mol Neurosci,J Neurochem及Cell等SCI源刊发表,主持国家自然科学基金面上项目1项。

目前主要研究方向为:1. 内源性大麻素在神经变性疾病中的作用及其机制;2. 脂类活性物质在神经元突触传递和可塑性中的作用及其机制;3. 病理性疼痛的外周及中枢机制的研究。

代表性研究论文:

1. Zou Z, Lu Y, Zha Y, Yang H (通讯作者). Endocannabinoid 2-Arachidonoylglycerol Suppresses LPS-induced Inhibition of A-type Potassium Channel Currents in Caudate Nucleus Neurons through CB1 receptor. J Mol Neurosci. 2016, 59(4):493-503

2. Zou Z, Lu Y, Dong M, Yang H (通讯作者). Effect of Homocysteine on voltage-gated sodium channel currents in Primary Cultured Rat Caudate Nucleus Neurons and its modulation by 2-Arachidonylglycerol. J Mol Neurosci. 2015, 57(4):477-485.

3. Dong M, Lu Y, Zou Z, Yang H (通讯作者) Monoacylglycerol lipase inhibitor protects primary cultured neurons against homocysteine-induced impairments in rat caudate nucleus through COX-2 signaling. Life Sci. 2015, 138: 64–71.

4. Dong M, Lu Y, Zha Y, Yang H (通讯作者). Endocannabinoid 2-Arachidonylglycerol Protects Primary Cultured Neurons Against Homocysteine-Induced Impairments in Rat Caudate Nucleus Through CB1 Receptor. J Mol Neurosci. 2015, 55(2):500-508.

5. Lu Y, Peng F, Dong M, Yang H (通讯作者). Endocannabinoid 2-arachidonylglycerol protects primary cultured neurons against LPS-induced impairments in rat caudate nucleus. J Mol Neurosci. 2014,54(1):49-58.

6. Chen R, Zhang J, Fan N, Teng ZQ, Wu Y, Yang H, Tang YP, Sun H, Song Y, Chen C.Δ9-THC-caused synaptic and memory impairments are mediated through COX-2 signaling. Cell. 2013, 155(5): 1154-65.

7. Yang H, Zhang J, Breyer RM, Chen C. Altered hippocampal long-term synaptic plasticity in mice deficient in the PGE2 EP2 receptor. J Neurochem. 2009,108:295-304.

8. Yang H and Chen C. Cyclooxygenase-2 in Synaptic Signaling. Current Pharmaceutical Design. 2008, 14 (14): 1443-1451.

9. Yang H, Zhang J, Andreasson K, Chen C. COX-2 oxidative metabolism of endocannabinoids augments hippocampal synaptic plasticity. Mol Cell Neurosci. 2008, 37 (4): 682-95.

10. Yang HW, Zhou LJ, Hu NW, Xin WJ, Liu XG. Activation of spinal d1/d5 receptors induces late-phase LTP of C-fiber-evoked field potentials in rat spinal dorsal hon. J Neurophysiol.2005, 94 (2): 961-967.

11. Yang HW, Hu XD, Zhang HM et al. Roles of CaMKII, PKA and PKC in the Induction and Maintenance of LTP of C-Fiber Evoked Field Potentials in Rat Spinal Dorsal Horn. J Neurophysiol. 2004, 91 (3): 1122-1133.

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