罗春艳，女，中共党员，博士，副教授，硕士生导师，毕业于华中科技大学遗传学专业。为2017年bat365中文官方网站引进的高层次学术水平双星人才，基础医学院生物病原与免疫学系教师，感染与炎症损伤研究所成员。主要研究方向与研究领域：人类心血管疾病遗传学，研究心血管疾病（包括冠心病、心梗、心律失常、先天性心脏病等）致病基因、易感基因的定位克隆、致病分子机制；以及致病机理中的感染与慢性炎症作用和参与的信号通路等功能研究及新靶点药物治疗。近年来主持完成国家自然科学基金青年科学基金项目1项，湖北省自然科学基金青年项目1项，bat365中文官方网站高层次人才科研启动基金项目1项；近几年共发表SCI论文14篇，其中第一作者/通讯作者9篇。在Biochim Biophys Acta-Mol Basis Dis, Physiol Genomics, Gene, Mol Genet Genomics, Front Biosci (Landmark Ed), Toxicol Sci, PLoS Genet, Nat Genet, J Mol Cell Cardiol等杂志上均发表过文章。目前承担bat365体育细胞生物学和医学遗传学的教学与科研工作。
拟招生方向：基础医学（学术型硕士），临床医学（学术型硕士）
欢迎报考！
联系方式：luochunyan1008@163.com或luochunyan@ctgu.edu.cn, QQ：276310867
主持/参与的科研项目：
1. 国家自然科学基金青年科学基金项目，（81900319），ADTRP调控ApoB/Collagen VII/LEPR介导心肌纤维化影响冠心病的分子机制研究、2020/01-2022/12，结题，主持
2. 湖北省自然科学基金青年项目，（2018CFB155），低密度脂蛋白（LDL）影响冠心病易感基因ADTRP功能的分子机制研究、2018/01-2019/12，结题，主持
3. bat365中文官方网站高层次人才科研启动基金项目，（20171106），冠心病易感基因ADTRP的功能研究，2017/09-2020/08，结题，主持
4. 国家自然科学基金青年项目，（81800550），运用Hes1 decoy ODN干预Hes1和miR-23b/27b/24-1基因簇之间的调节环进而逆转肝纤维化的研究， 2019/ 01-2021/12，结题，参与
代表性SCI论文：
1. Chunyan Luo#, Decheng Wang#, Weifeng Huang#, Yinhong Song#, Lisha Ge, Xinyue Zhang, Lixue Yang, Jiao Lu, Xiancong Tu, Qiuyun Chen, Jian Yang*, Chengqi Xu*, Qing Wang*. Feedback regulation of coronary artery disease susceptibility gene ADTRP and LDL receptors LDLR/CD36/LOX-1 in endothelia cell functions involved in atherosclerosis. Biochim Biophys Acta-Mol Basis Dis. 2021 Jul 1;1867(7):166130. doi: 10.1016/j.bbadis.2021.166130. Epub 2021 Mar 18. (IF=5.187, First author, JCR分区: Q1)
2. Chunyan Luo#, *, Bo Tang#, Subo Qin#, Chengfu Yuan, Youqin Du, Jian Yang*. GATA2 regulates the CAD susceptibility gene ADTRP rs6903956 through preferential interaction with the G allele. Mol Genet Genomics. 2021 Jul;296(4):799-808. doi: 10.1007/s00438-021-01782-1. Epub 2021 Apr 15. (First author and Corresponding author, IF=3.291, JCR分区: Q2)
3. Chunyan Luo#, Elisabeth Pook#, Fan Wang#, Stephen R. Archacki#, Bo Tang#, Weiyi Zhang#, Jing-Shan Hu#, Jian Yang#, Kirsten Leineweber, Martin Bechem, Weifeng Huang, Yinhong Song, Shing-Hu Cheung#, Volker Laux, Tie Ke, Xiang Ren, Xin Tu, Qiuyun Chen*, Qing Kenneth Wang*, Chengqi Xu*. ADTRP regulates TFPI expression via transcription factor POU1F1 involved in coronary artery disease. Gene. 2020 Aug 30;753:144805. doi: 10.1016/j.gene.2020.144805. Epub 2020 May 20. (IF=2.984, First author, JCR分区: Q2)
4. Chunyan Luo#, *, Yuwen Ruan#, Peixue Sun#, Haoran Wang#, Weihua Yang#, Yuankai Gong, Decheng Wang*. The Role of Transcription Factors in Coronary Artery Disease and Myocardial Infarction. Front Biosci (Landmark Ed). 2022 Dec 21;27(12):329. doi: 10.31083/j.fbl2712329. (IF=3.115, First author and Corresponding author, JCR分区: Q2)
5. Chunyan Luo#, Elisabeth Pook#, Bo Tang#, Weiyi Zhang#, Sisi Li#, Kirsten Leineweber, Shing-Hu Cheung, Qiuyun Chen, Martin Bechem, Jing-Shan Hu, Volker Laux*, Qing Kenneth Wang*. Androgen inhibits key atherosclerotic processes by directly activating ADTRP transcription. Biochim Biophys Acta-Mol Basis Dis. 2017 Sep;1863 (9):2319-2332. (IF=5.476, First author, JCR分区: Q1)
6. Chunyan Luo#, Fan Wang#, Xiang Ren#, Tie Ke#, Chengqi Xu#, Bo Tang, Subo Qin, Yufeng Yao, Qiuyun Chen*, Qing Kenneth Wang*. Identification of a molecular signaling gene-gene regulatory network between GWAS susceptibility genes ADTRP and MIA3/TANGO1 for coronary artery disease. Biochim Biophys Acta-Mol Basis Dis. 2017 Jun;1863(6):1640-1653. (IF=5.476, First author, JCR分区: Q1)
7. Chunyan Luo#, Fan Wang#, Subo Qin, Qiuyun Chen, Qing Kenneth Wang*. Coronary artery disease susceptibility gene ADTRP regulates cell cycle progression, proliferation, and apoptosis by global gene expression regulation. Physiol Genomics. 2016 Aug 1; 48(8):554-564. (IF=3.044, First author, JCR分区: Q2)
8. Lisong Shi#, Chunyan Luo#, Mairaj K. Ahmed, Ali B. Attaie, Xiaoqian Ye*. Novel mutations in EVC cause aberrant splicing in Ellis-van Creveld syndrome. Mol Genet Genomics. 2016 Apr; 291(2):863-872. (IF=2.979, Co-first author, JCR分区: Q2)
9. Xing Liu#, Hongqian Zhao#, Chunyan Luo#, Debin Du, Jinlong Huang, Quan Ming, Fen Jin, Decheng Wang*, Weifeng Huang*. Acetaminophen Responsive miR-19b Modulates SIRT1/Nrf2 Signaling Pathway in Drug-Induced Hepatotoxicity. Toxicol Sci. 2019 Aug 1;170(2):476-488. doi: 10.1093/toxsci/ kfz095. (IF=4.181, Co-first author, JCR分区: Q1)
10. Ping Ouyang#, Elizabeth Saarel, Ying Bai, Chunyan Luo, Qiulun Lv, Yan Xu, Fan Wang, Chun Fan, Adel Younoszai, Qiuyun Chen, Xin Tu*, Qing Kenneth Wang*. A de novo mutation in NKX2.5 associated with atrial septal defects, ventricular noncompaction, syncope and sudden death. Clin Chim Acta. 2011 Jan 14;412(1-2):170-175. (IF=2.873, Co-author)
11. Yabo Li#, Hyosuk Cho#, Fan Wang, Oriol Canela-Xandri, Chunyan Luo, Konrad Rawlik, Stephen Archacki, Chengqi Xu, Albert Tenesa, Qiuyun Chen*, Qing Kenneth Wang*. Statistical and Functional Studies Identify Epistasis of Cardiovascular Risk Genomic Variants From Genome-Wide Association Studies. J Am Heart Assoc. 2020 Apr 7;9(7):e014146. (IF=4.66, Co-author)
12. Bo Tang#, Yushang Hu#, Zhijie Wang#, Chen Cheng#, Pengyun Wang#, Lina Liang, Hongbo Xiong, Chunyan Luo, Chengqi Xu, Qiuyun Chen*, Qing Kenneth Wang*. UBC9 regulates cardiac sodium channel Nav1.5 ubiquitination, degradation and sodium current density. J Mol Cell Cardiol. 2019 Apr;129:79-91. (IF=5.055, Co-author)
13. Yufeng Huang#, Chuchu Wang#, Yufeng Yao#, Xiaoyu Zuo#, Shanshan Chen#, Chengqi Xu, Hongfu Zhang, Qiulun Lu, Le Chang, Fan Wang, Pengxia Wang, Rongfeng Zhang, Zhenkun Hu, Qixue Song, Xiaowei Yang, Cong Li, Sisi Li, Yuanyuan Zhao, Qin Yang, Dan Yin, Xiaojing Wang, Wenxia Si, Xiuchun Li, Xin Xiong, Dan Wang, Yuan Huang, Chunyan Luo, Jia Li, Jingjing Wang, Jing Chen, Longfei Wang, Li Wang, Meng Han, Jian Ye, Feifei Chen, Jingqiu Liu, Ying Liu, Gang Wu, Bo Yang, Xiang Cheng, Yuhua Liao, Yanxia Wu, Tie Ke, Qiuyun Chen, Xin Tu, Robert Elston Elston, Shaoqi Rao, Yanzong Yang*, Yunlong Xia, Qing K. Wang*. Molecular Basis of Gene-Gene Interaction: Cyclic Cross-Regulation of Gene Expression and Post-GWAS Gene-Gene Interaction Involved in Atrial Fibrillation. PLoS Genet. 2015 Aug 12;11(8):e1005393. (IF=6.661, Co-author)
14. Fan Wang#, Cheng-Qi Xu#, Qing He#, Jian-Ping Cai#, Xiu-Chun Li#, Dan Wang#, Xin Xiong#, Yu-Hua Liao#, Qiu-Tang Zeng#, Yan-Zong Yang#, Xiang Cheng#, Cong Li, Rong Yang, Chu-Chu Wang, Gang Wu, Qiu-Lun Lu, Ying Bai, Yu-Feng Huang, Dan Yin, Qing Yang, Xiao-Jing Wang, Da-Peng Dai, Rong-Feng Zhang, Jing Wan, Jiang-Hua Ren, Si-Si Li, Yuan-Yuan Zhao, Fen-Fen Fu, Yuan Huang, Qing-Xian Li, Sheng-Wei Shi, Nan Lin, Zhen-Wei Pan, Yue Li, Bo Yu, Yan-Xia Wu, Yu-He Ke, Jian Lei, Nan Wang, Chun-Yan Luo, Li-Ying Ji, Lian-Jun Gao, Lei Li, Hui Liu, Er-Wen Huang, Jin Cui, Na Jia, Xiang Ren, Hui Li, Tie Ke, Xian-Qin Zhang, Jing-Yu Liu, Mu-Gen Liu, Hao Xia, Bo Yang, Li-Song Shi, Yun-Long Xia, Xin Tu*, Qing K Wang*. Genome-wide association identifies a susceptibility locus for coronary artery disease in the Chinese Han population. Nat Genet. 2011 Mar 6; 43(4):345-349. (IF=37.5, Co-author)
