余祥，男，工学博士，校聘副教授，硕士生导师，省级人才。主要研究方向：1) 仿生性纳米载体在肝脏慢性疾病和肿瘤免疫治疗中的应用研究；2) 宿主防御多肽诱导肿瘤细胞焦亡机制研究；3）活体动态光学成像观察肿瘤免疫治疗效应及分子机制研究。现承担湖北省自然科学基金1项，主持bat365中文官方网站高层次人才项目计划1项，参与包括国家重点研发计划重点专项在内的科研项目3项。以第一或共同第一发表Nature子刊（IF > 10）3篇。
拟招生方向：基础医学（学术型硕士） 欢迎报考！
联系方式：yuxiangwl2008@sina.com，13125076640，QQ：936911200
主持的科研项目：
1. 湖北省自然科学基金青年项目（2020CFB371），基于红细胞膜的仿生性纳米载体对乳腺癌转移的诊疗研究，2020/03-2022/03，5.0万元，在研，主持;
2. bat365中文官方网站高层次人才科研启动金（8203002），2020/07-2023/06，50万，在研，主持。
参与的科研项目：
1. 科技部国家重点研发计划重点专项（2017YFA0700400），肝脏三维结构与功能信息的精准介观测量，2018/05-2023/04，2776 万元，在研，参与；
2. 华中科技大学科学技术发展院面上项目（培育基金），多肽脂质纳米颗粒抗肿瘤肝转移效应及机制研究，2018/01-2020/12，10 万，已结题，主要负责人；
3. 国家自然科学基金青年基金（31700808），自发性肿瘤免疫清除活体可视化研究，2018/01-2020/12，25 万，已结题，参与。
代表性论著：
1. Xiang Yu, Lu Chen, Jianqiao Liu, Bolei Dai, Guoqiang Xu, Guanxin Shen, Qingming Luo, Zhihong Zhang. Immune Modulation of Liver Sinusoidal Endothelial Cells by Melittin Nanoparticles Suppresses Liver Metastasis. Nature Communications, 2019, 10(1): 574. (JCR一区, IF = 12.12, First author).
2. Xiang Yu*, Yanfeng Dai*, Yifan Zhao, Shuhong Qi Lisen Lu, Qingming Luo, Zhihong Zhang. Melittin-lipid nanoparticles as a whole-cell in situ nanovaccine that targets to lymph node and elicits a systemic antitumor immune response. Nature Communications,2020, 11(1), 1-14. (JCR一区, IF = 12.12, Co-first author).
3. Yanfeng Dai1*, Xiang Yu*, Jianshuang Wei*, Fanxin Zeng, Yiran Li, Xiaoquan Yang, Qingming Luo, Zhihong Zhang. Metastatic status of sentinel lymph nodes in breast cancer determined with photoacoustic microscopy via dual-targeting nanoparticles. Light: Science & Applications. 2020, 9: 164. https://doi.org/10.1038/s41377-020-00399-0. (JCR一区, IF = 13.71, Co-first author).
其他参与文章：
1. Lu Chen, Hao Zheng, Xiang Yu, Lei Liu, Heli Li, Huifen Zhu, Zhihong Zhang, Guanxin Shen, Ping Lei. Tumor-secreted GRP78 promotes the establishment of a pre-metastatic niche in the liver microenvironment. Frontiers in Immunology. 2020, accepted. doi: 10.3389/fimmu.2020.584458. (JCR一区, IF = 5.08, Co-author).
2. Lisen Lu, Shuhong Qi, Yuzhou Chen, Haiming Luo, Songlin Huang, Xiang Yu, Qingming Luo, Zhihong Zhang. Targeted immunomodulation of inflammatory monocytes across the blood-brain barrier by curcumin-loaded nanoparticles delays the progression of experimental autoimmune encephalomyelitis. Biomaterials, 2020, 245: 119987. (JCR一区, IF = 10.31, Co-author).
3. Shuhong Qi, Lisen Lu, Feifan Zhou, Yuzhou Chen, Mengli Xu, Lu Chen, Xiang Yu, Chen Wei R., Zhihong Zhang. Neutrophil infiltration and whole-cell vaccine elicited by N-dihydrogalactochitosan combined with NIR phototherapy to enhance antitumor immune response and T cell immune memory. Theranostics, 2020, 10(4): 1814-1832. (JCR一区, IF = 8.58, Co-author).
4. Qian Yuan, Qiao Sha, Dai Yanfeng, Guoqiang Xu, Bolei Dai, Lisen Lu, Xiang Yu, Qingming Luo, Zhihong Zhang. Molecular-Targeted Immunotherapeutic Strategy for Melanoma via Dual-Targeting Nanoparticles Delivering Small Interfering RNA to Tumor-Associated Macrophages. ACS Nano, 2017, 11(9): 9536-9549. (JCR一区, IF = 14.59, Co-author).
